ISSUE

Volume-I

, Issue-I

(FALL 2016)

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01 - An Insight About the Drug Release Mechanisms from Different Dosage Forms

http://dx.doi.org/10.31703/gdddr.2016(I-I).01
10.31703/gdddr.2016(I-I).01
Published : Dec 2016

Abstract

    A process in which drug comes out from drug product and exposed to ADME and finally become accessible for pharmacological activity is known as drug release and mechanism involves the study of its rate and factors influencing its rate. Factors influencing the rate of drug release are drug related, polymer related and formulation variables. Drug delivery systems are discriminated on the basis of way... Details

    Drug Release Mechanisms, Dosage Forms, Drugs, Parenteral, Diffusion

    (1) Hafsa Shahid
    a Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Ayesha Ahmed
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Ammarah Ashraf
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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02 - Pharmacokinetic Modeling Concepts: Compartmental and Non-compartmental approach

http://dx.doi.org/10.31703/gdddr.2016(I-I).02
10.31703/gdddr.2016(I-I).02
Published : Dec 2016

Abstract

    Pharmacokinetic modeling helps to estimate the ADME parameters of all the natural and synthetic drug substances in humans and animals. There are two types of approaches for predicting the kinetic processes inside the body i.e., model approach and model independent approach. Model approach is further divided into compartmental and physiological models and model independent approach consists of non-... Details

    Pharmacokinetic, Models, Compartments, Parameters, Drug, Concentration

    (1) Duaa Aslam Chaudhry
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Urooj Fatima
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Kainat Waqar
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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03 - Oral Drug Delivery to the Experimental Animals, A Mini Review

http://dx.doi.org/10.31703/gdddr.2016(I-I).03
10.31703/gdddr.2016(I-I).03
Published : Dec 2016

Abstract

    In several pharmacologic, pharmacology, and alternative medicine studies, oral administration of medication or test substances to experimental animals is needed. It is clinically sound and recommended to administer test substances to experimental animals along the same route that they are taken or expected to be taken by humans as general bioavailability; the pharmacology and pharmacology paramete... Details

    Oral Administration, Experimental Animal, Cannula

    (1) Arif Paiman
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Ahmad Mohammadi
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Rafia Inam
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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04 - A Comprehensive Insight on Pharmacokinetics

http://dx.doi.org/10.31703/gdddr.2016(I-I).04
10.31703/gdddr.2016(I-I).04
Published : Dec 2016

Abstract

    Pharmacokinetics can be defined as what the body does to a drug. The basic parameters of pharmacokinetics are discussed here including absorption, distribution, metabolism, and excretion. Characteristics and pathways taken by these drugs are determined by these parameters. The mechanism followed by these parameters are also discussed. Furthermore, the factors affecting these parameters including p... Details

    Pharmacokinetics, Absorption, Distribution, Metabolism

    (1) Urooj Naseem
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Fatima Iqbal
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Gul Shahnaz
    Chairperson, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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05 - Statistical Moment Theory and Non-Compartmental Analysis

http://dx.doi.org/10.31703/gdddr.2016(I-I).05
10.31703/gdddr.2016(I-I).05
Published : Dec 2016

Abstract

    Mathematical model a numerical classification of the biological framework and utilized to state quantitative connections. A pharmacokinetic compartment is a numerical idea that portrays a space in the body that medication seems to possess These models just mediate the test information and permit an experimental equation for the assessment of medication focus with time. A non- compartmental model i... Details

    Non-Compartmental Model, the Non-Compartmental Analysis Statistical Moment Theory, the Non-Compartmental Analysis, Types of Models

    (1) Samina Zehussain
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Muhammad Ilyas
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Abdullah
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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