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ANTIBACTERIAL ANTIFUNGAL AND PHYTOTOXIC PHARMACOLOGICAL PROFILING OF DIFFERENT EXTRACTS OF LESPEDESEA GERARDIANA

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03 Pages : 23-33

http://dx.doi.org/10.31703/gdddr.2023(VIII-III).03      10.31703/gdddr.2023(VIII-III).03      Published : Sep 2023

Antibacterial, Antifungal and Phytotoxic Pharmacological Profiling of Different Extracts of Lespedesea Gerardiana

Abstract

    This study is based on phytochemical properties of L. gerardiana, as well as the pharmacological and biological activities of crude methanolic extract (Crd. MeOH Ext.) and other fractions. A range of pharmacological and biological activities, such as antibacterial, antifungal, phytotoxic, were examined in Crd. MeOH Extract and different plant fractions. The results of the pharmacological and biological examinations showed that the chloroform (CHCl3) fraction had good antibacterial activity against Salmonella typhi (48.0%), Bacillus cereus, Proteus merabilus (50.0%), and Klebsiella pneumoniae (57.1%). Also demonstrating strong (55.5%) antibacterial activity against S. typhi was the n‐hexane fraction. Low phytotoxicity was demonstrated by the plant materials at 1000 and 100μg/ml concentrations.

    Methanolic Extract, Salmonella Typhi, Bacillus Cereus, Proteus Merabilus

    (1) Bushra Rehman
    Assistant Professor, Institute of Biotechnology and Microbiology, Bacha Khan University, Charsadda, KP, Pakistan.
    (2) Hajra Afira Ahmad
    Assistant professor, Department of MLT and Biotechnology, University of Bannu, KP, Pakistan.
    (3) Aiman Umar
    Assistant Professor, Department of Food and Nutrition, Shaheed Benazir Bhutto Women University, Peshawar, KP, Pakistan.
    (4) Dur-E-Najaf Khan
    Lecturer, Department of Pharmacy, Bacha Khan University, Charsadda, KP, Pakistan.
    (5) Muhammad Kashif
    Research officer, Institute of Soil and Environmental Sciences, University of Agriculture, Faisalabad, Punjab, Pakistan.
    (6) Numan Saleh Zada
    Senior Scientific Officer, Pakistan Council of Scientific and Industrial Research (PCSIR) Laboratories Complex, Peshawar, KP, Pakistan.
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Cite this article

APA

    APA : Rehman, B., Ahmad, H. A., & Umar, A. (2023). Antibacterial, Antifungal and Phytotoxic Pharmacological Profiling of Different Extracts of Lespedesea Gerardiana. Global Drug Design & Development Review, VIII(III), 23-33. https://doi.org/10.31703/gdddr.2023(VIII-III).03

CHICAGO

    CHICAGO : Rehman, Bushra, Hajra Afira Ahmad, and Aiman Umar. 2023. "Antibacterial, Antifungal and Phytotoxic Pharmacological Profiling of Different Extracts of Lespedesea Gerardiana." Global Drug Design & Development Review, VIII (III): 23-33 doi: 10.31703/gdddr.2023(VIII-III).03

HARVARD

    HARVARD : REHMAN, B., AHMAD, H. A. & UMAR, A. 2023. Antibacterial, Antifungal and Phytotoxic Pharmacological Profiling of Different Extracts of Lespedesea Gerardiana. Global Drug Design & Development Review, VIII, 23-33.

MHRA

    MHRA : Rehman, Bushra, Hajra Afira Ahmad, and Aiman Umar. 2023. "Antibacterial, Antifungal and Phytotoxic Pharmacological Profiling of Different Extracts of Lespedesea Gerardiana." Global Drug Design & Development Review, VIII: 23-33

MLA

    MLA : Rehman, Bushra, Hajra Afira Ahmad, and Aiman Umar. "Antibacterial, Antifungal and Phytotoxic Pharmacological Profiling of Different Extracts of Lespedesea Gerardiana." Global Drug Design & Development Review, VIII.III (2023): 23-33 Print.

OXFORD

    OXFORD : Rehman, Bushra, Ahmad, Hajra Afira, and Umar, Aiman (2023), "Antibacterial, Antifungal and Phytotoxic Pharmacological Profiling of Different Extracts of Lespedesea Gerardiana", Global Drug Design & Development Review, VIII (III), 23-33

TURABIAN

    TURABIAN : Rehman, Bushra, Hajra Afira Ahmad, and Aiman Umar. "Antibacterial, Antifungal and Phytotoxic Pharmacological Profiling of Different Extracts of Lespedesea Gerardiana." Global Drug Design & Development Review VIII, no. III (2023): 23-33. https://doi.org/10.31703/gdddr.2023(VIII-III).03