ISSUE

Volume-II

, Issue-I

(FALL 2017)

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01 - Role of Computer Aided Drug Design in Modern Drug Discovery and Pharmacokinetic

http://dx.doi.org/10.31703/gdddr.2017(II-I).01
10.31703/gdddr.2017(II-I).01
Published : Dec 2017

Abstract

    In modern day, Data on different diseases and drug substances with their properties like modification, side effects, and dose requires documentation data and building library exploring, such library with vast information in every aspect needs computational methods used in CADD. Recognition of specific targets for the drug tested and defining pharmacological activity of a drug candidate based on th... Details

    Computer Aided Drug Design, Pharmacokinetics, Computational Methods, Drug Discovery, Novel Drug Candidate, Target -Drug Interaction

    (1) Arif Paiman
    Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Ahmad Mohammad
    Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan
    (3) Mubashar Rehman
    Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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03 - A Literature Review of the Physicochemical, Physiological and Pharmaceutical Co

http://dx.doi.org/10.31703/gdddr.2017(II-I).03
10.31703/gdddr.2017(II-I).03
Published : Dec 2017

Abstract

    Oral route of drug administration is the most common among all routes and hence their pharmacokinetic and pharmacodynamic factors are substantial to study. Among such factors, GIT absorption is the key factor in new drug development affecting the efficacy as well as safety of the drug. Different protocols have now been developed for the usage of in vitro also the in vivo as well as in situ methods... Details

    Absorption, Gastro-Intestinal Tract, Transport, Bioavailability, Drug Dissolution, Diffusion, Drug Stability

    (1) Rabia Mazhar
    Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
    (2) Fariah Qaiser
    Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
    (3) Sana Ali Zahra
    Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
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04 - Strategies and Techniques of Drug Discovery from Natural Products

http://dx.doi.org/10.31703/gdddr.2017(II-I).04
10.31703/gdddr.2017(II-I).04
Published : Dec 2017

Abstract

    New drugs are mostly obtained from Natural sources. The traditional and ethic medicines have provided evidence on the therapeutic properties and resulted in some distinguished drug discovery of natural products. The microorganisms and the endogenous active materials from human or animal have also become a significant approach to the discovery of a drug. Bioinformatics and artificial intelligence h... Details

    Essential Products, Drug Development and Design, Discovery, Strategies, Omics.

    (1) Parniya Akbar Ali
    Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
    (2) Farah Hanif
    Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
    (3) Hosna Nettour
    Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
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05 - A Literature Study of IPQC (In Process Quality Control) tests and FDF (Finished

http://dx.doi.org/10.31703/gdddr.2017(II-I).05
10.31703/gdddr.2017(II-I).05
Published : Dec 2017

Abstract

    This study was conducted to evaluate both the in-process quality control tests as well as the finished dosage form tests for a parenteral product. Furthermore, all the processes from the purchase of API to marketing of product were studied. A batch of Adicovil was taken Adicovil was taken as an example, it is small volume parenteral of 2ml ampoule that is studied to evaluate its efficacy and stabi... Details

    Parenteral, IPQC, stability tests, FDF, physical tests, chemical tests.

    (1) Ayesha Sabir
    Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
    (2) Syeda Komal Fatima
    Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
    (3) Asma Kaleem
    Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.
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