ISSUE

Volume-III

, Issue-I

(FALL 2018)

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01 - Methods to Intra-Peritoneal and Subcutaneous Administration on Experimental Anim

http://dx.doi.org/10.31703/gdddr.2018(III-I).01
10.31703/gdddr.2018(III-I).01
Published : Dec 2018

Abstract

    Parenteral site of administration of drug provides several advantages. In subcutaneous administration of the drug mainly move to the capillaries from the site of action. However, in case of the intraperitoneal administration the peritoneal cavity of is the target. Different experimental animal requires certain criteria to deliver the dose of the drugs. All the parameter is vital to perform experim... Details

    Liquid Drug, Experimental Animal, Subcutaneous, Intraperitoneal

    (1) Shahrukh Asif
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Hafsa Abbas
    Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Mubashar Rehman
    Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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02 - Translational Medicine and Drug Discovery: A Mini Review

http://dx.doi.org/10.31703/gdddr.2018(III-I).02
10.31703/gdddr.2018(III-I).02
Published : Dec 2018

Abstract

    There are a very large number of drugs that enter in the clinical trial phase but only a fraction of them is able to get their place in market. For a drug to reach at a phase of clinical trial requires a huge effort of research and a very large investment. Translational medicine, a relatively new discipline, uses the novel techniques that not only lower the risk of investment failure, but also foc... Details

    Clinical Trials, Biomarkers, Alzheimer's, Fucoidin, Preclinical Modes, Bone Disorders

    (1) Muhammad Saadullah Khan
    Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Farwa Shahid
    Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Arooj Shahid
    Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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03 - Individualization of Dosage Regimen-an Approach Towards Improved Clinical Outcom

http://dx.doi.org/10.31703/gdddr.2018(III-I).03
10.31703/gdddr.2018(III-I).03
Published : Dec 2018

Abstract

    Dosage regimen plays the most important role in obtaining the desired therapeutic outcomes. The focus perpetually is on the design of doses, their intervals and duration to acquire the optimum response. Many factors like age, gender, weight, body surface area, pathological state play a role in formulating these regimens and each factor is given importance in deciding regimen that gives the optimum... Details

    Dosage Regimen, Therapeutic Drug Monitoring, Multiple Dosage Regimen

    (1) Syed Faaez Ul Hassan Naqvi
    Undergraduate Students (Final Year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Tehreem Haider
    Undergraduate Students (Final Year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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04 - Quality Determination (In-process & Finished product Quality Testing Parameters)

http://dx.doi.org/10.31703/gdddr.2018(III-I).04
10.31703/gdddr.2018(III-I).04
Published : Dec 2018

Abstract

    Triamcinolone acetonide is an antiinflammatory drug that has been used for more than 50 years for the treatment of various inflammatory disorders including the arthritis & gout etc. Moreover, in recent years its use has been rapidly increased for the treatment of retinal vasculature disease and Uveitis, periocular and intraocular treatment. This review summarizes the whole manufacturing proces... Details

    Quality Control, Parenteral, In-Process, Triamcinolone Acetonide

    (1) Rana Muhammad Awais Khan
    Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Mubashar Rehman
    Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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05 - Pharmaceutical Nanotechnology: Bio-pharmaceutical Support in Candidate Drug Sele

http://dx.doi.org/10.31703/gdddr.2018(III-I).05
10.31703/gdddr.2018(III-I).05
Published : Dec 2018

Abstract

    Drug selection is one of the important steps in new drug development. There are multiple factors that contribute to new drug formulation. Biopharmaceutical considerations along with physiological and pharmaceutical parameters are more helpful in defining the process. Various GIT restrictive barriers are challenges for many new drug developments. New drug formulation advantages over the traditional... Details

    Drug screening, Drug development, Biopharmaceutical Aspects

    (1) Najam ul Hassan
    Pharm-D (Gold Medalist) ,Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Maria Naz Bakhtiari
    M.phil, Department of Pharmacy, The Islamia University of Bahawalpur, Punjab, Pakistan.
    (3) Dur E Nayab
    M.phil, Department of Pharmacy, The Islamia University of Bahawalpur, Punjab Pakistan.
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