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Volume-VIII

, Issue-II

(SPRING 2023)

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01 - Prevalence of Hypertension in Patients Presenting to Mardan Medical Complex for

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).01
10.31703/gdddr.2023(VIII-II).01
Published : Jun 2023

Abstract

    A major contributor to morbidity and mortality globally is hypertension. It is usually underdiagnosed. ABPM has a role in diagnosing this important entity in a general asymptomatic population. It was a descriptive cross-sectional study carried out at the Cardiac Diagnostic Centre of the Cardiology Department of MTI Mardan Medical Complex, where we reviewed our ABPM computer registry from June 2017... Details

    Hypertension, Mardan Medical Complex, ABPM, Cardiology, Heart

    (1) Noorul Hadi
    Assistant Professor, Cardiology Unit, MTI Mardan Medical Complex, Mardan, KP, Pakistan.
    (2) Shafiq Alam
    Assistant Professor, Cardiology Unit, MTI Mardan Medical Complex, Mardan, KP, Pakistan.
    (3) Asfandiyar
    Assistant Professor, Cardiology Unit, MTI Mardan Medical Complex, Mardan, KP, Pakistan.
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02 - Evaluation Of The Anti-Inflammatory Pharmacological Effects Of Artemisia Annua E

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).02
10.31703/gdddr.2023(VIII-II).02
Published : Jun 2023

Abstract

    Artemisia annua L. is acknowledged as a traditional medicinal plant bearing potent antimalarial, antileishmanial, antibacterial, antifungal and antioxidant potential. Therefore, this study was carried out to explore the anti-inflammatory impact of A. annua both in vitro and in vivo in rabbit models. We procured fresh A. annua plant material from local nurseries and Artemisinin was extracted from i... Details

    Anti-inflammatory, Cytokines, Inflammatory mediators, Interleukines, Potent drugs

    (1) Muhammad Saqib
    Institute of Physiology and Pharmacology, University of Agriculture Faisalabad, Punjab, Pakistan.
    (2) Samiyah Tasleem
    Department of Microbiology, FUUAST and University of Karachi, Sindh, Pakistan.
    (3) Kamran Afzal
    Senior Instructor, Department of Biological and Biomedical Sciences Aga Khan University, Pakistan.
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03 - Emerging Trends in Nano-Theranostics: Platinum-based Drug Delivery Systems for C

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).03
10.31703/gdddr.2023(VIII-II).03
Published : Jun 2023

Abstract

    Nanotechnology is the most common and frequently used technology that aims to improve the efficacy of medical procedures, sometimes known as Nanomedicine. With their impressive pharmacological efficacy as nanomedicines and delivery systems, nano materials have been recognized as attractive diagnostic and chemotherapeutic tools to treat diseases. To treat a wide range of solid malignant tumors, Dru... Details

    Nanomedicines, Platinum Drugs, Chemotherapeutic, Pharmacological drugs

    (1) Samia Asif
    Department of Chemistry, School of Science, University of Management and Technology, Lahore, Punjab, Pakistan.
    (2) Sammia Shahid
    Department of Chemistry, School of Science, University of Management and Technology, Lahore, Punjab, Pakistan.
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04 - Investigation of Placental Modifications in Patients with Preeclampsia: Examinat

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).04
10.31703/gdddr.2023(VIII-II).04
Published : Jun 2023

Abstract

    Preeclampsia can have an effect on both the mother's health as well as the unborn child, and it only occurs during gestation and after delivery. Proteins in urine as well as high levels of blood pressure are two signs of this disease that advances swiftly. The study's goal was to look at the histology and to examine for ultrastructural alterations in the placentas of preeclampsia-affected pregnan... Details

    Placental Modification, Preeclampsia, Microscopy, Ultrastructural Alteration

    (1) Nighat Ara
    Associate Professor, Department of Anatomy, Nowshera Medical College, Nowshera, KP, Pakistan.
    (2) Waqas Ali
    Senior Lecturer, Department of Anatomy, Nowshera Medical College, Nowshera, KP, Pakistan.
    (3) Muhammad Kabir Khan Afridi
    Lecturer, Department of Anatomy, Khyber Medical University Institute of Medical Sciences, Kohat, KP, Pakistan.
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05 - Serum Levels of Erythropoietin in Patients with Anemia and Chronic Obstructive P

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).05
10.31703/gdddr.2023(VIII-II).05
Published : Jun 2023

Abstract

    Nanotechnology is the most common and frequently used technology that aims to improve the efficacy of medical procedures, sometimes known as Nanomedicine. With their impressive pharmacological efficacy as nanomedicines and delivery systems, nano materials have been recognized as attractive diagnostic and chemotherapeutic tools to treat diseases. To treat a wide range of solid malignant tumors, Dru... Details

    Nanomedicines, Platinum Drugs, Chemotherapeutic, Pharmacological drugs

    (1) Adam Fazli Rabbi
    Demonstrator, Department of Biochemistry, Rawal Institute of Health Sciences, Islamabad, Pakistan.
    (2) Malaika Khan
    Demonstrator, Department of Physiology, Rawal Institute of Health Sciences, Islamabad, Pakistan.
    (3) Maryam Shaid Ullah
    Department of Physiology, Khyber Medical University, Peshawar, KP, Pakistan.
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06 - Association of Hydrocephalus Etiology, Infection Rate, and Age at Shunt Placemen

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).06
10.31703/gdddr.2023(VIII-II).06
Published : Jun 2023

Abstract

    his retrospective research examined 150 people five years after their initial cerebral fluid shunt. Hydrocephalus aetiology, infection rates, and shunt age were investigated. Medical records were evaluated for hydrocephalus aetiology, surgical evaluations of under-one-year-olds, infection rates, and treatments. Statistics examined hydrocephalus aetiology, infection rate, and age. Meningomyelocele ... Details

    Hydrocephalus, Cerebral Fluid Shunt, Retrospective Analysis, Aetiology, Infection Rate, Age at Shunt Placement, Meningomyelocele, Acetazolamide, Furosemide

    (1) Muhammad Idris Khan
    Assistant Professor, Department of Neurosurgery, Khyber Teaching Hospital, Peshawar, KP, Pakistan.
    (2) Adnan Munir
    Trainee Registrar, Department of Neurosurgery, Khyber Teaching Hospital, Peshawar, KP, Pakistan.
    (3) Syed Aziz
    Medical Officer, Department of Neurosurgery, Khyber Teaching Hospital, Peshawar, KP, Pakistan.
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07 - Evolutionary Study of DGAT1 Gene Indicates the Presence of Positive Selection in

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).07
10.31703/gdddr.2023(VIII-II).07
Published : Jun 2023

Abstract

    This study was focused on the evolving role of DGAT1 using phylogenetic analysis. DGAT1 was retrieved from available databases of 37 mammalian genomes to detect signatures of positive selection in individual codons. Evolutionary analyses likelihood (REL), fast unconstrained Bayesian approximation (FUBAR), and Mixed-effects model evolution (MEME). REL detected 3 positive selection sites (at 109, 19... Details

    Evolutionary Study, DGAT1, Mammals, Positive Selection Variation

    (1) Bushra Rehman
    Assistant Professor, Institute of Biotechnology and Microbiology, Bacha Khan University, Charsadda, KP, Pakistan.
    (2) Rabiya Nasir
    Assistant Professor, Center of Excellence in Marine Biology, Karachi, Sindh, Pakistan.
    (3) Hira Ikram
    Lecturer, Institute of Biotechnology and Microbiology, Bacha Khan University, Charsadda, KP, Pakistan.
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08 - An Experience of Supine PCNL in Tertiary Care Hospital in Gujranwala, Pakistan

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).08
10.31703/gdddr.2023(VIII-II).08
Published : Jun 2023

Abstract

    A prospective analytical study was conducted at the Urology Department of Gujranwala Teaching Hospital from January 2022 to April 2023. The aim was to experience the safety & efficacy of supine PCNL performed at tertiary care hospital at Gujranwala which is being performed in few centers in Pakistan. A total of 98 patients undergoing percutaneous nephrolithotomy (PCNL) were included in the stu... Details

    PCNL, Renal Stones, Tertiary Care Hospital

    (1) Khalid Hussain Hussain
    Assistant Professor (Head), Department of Urology, DHQ Teaching Hospital, Gujranwala, Punjab, Pakistan.
    (2) Maria Tariq
    PGR, Department of Urology, DHQ Teaching Hospital, Gujranwala, Punjab, Pakistan.
    (3) Ali Umair Tariq
    MBBS Student, Gujranwala Medical College, Gujranwala, Punjab, Pakistan.
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09 - Efficacy of Ultrasound‐Guided Double Lumen Central Venous Catheter

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).09
10.31703/gdddr.2023(VIII-II).09
Published : Jun 2023

Abstract

    The aim of the study was to compare the outcomes of ultrasound‐guided double‐lumen central venous catheter (DLC) insertion and without ultrasound guidance in reducing mechanical complications and bloodstream infections. This quasi‐experimental study was conducted at Urology Department in collaboration with the Anesthesia department at GMC Teaching Hospital Gu... Details

    Dialysis, DLC, Ultrasound

    (1) Khalid Hussain
    Assistant Professor & Head, Department of Urology, GMC /Gujranwala Teaching Hospital, Gujranwala, Punjab, Pakistan.
    (2) Attiq Ur Rehman Khan
    Assistant Professor, Department of Urology, GMC/ Gujranwala Teaching Hospital, Gujranwala, Punjab, Pakistan.
    (3) Salman Athar Qureshi
    Associate Professor, Department of Anesthesia, GMC/ Gujranwala Teaching Hospital, Gujranwala, Punjab, Pakistan.
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10 - Quasi-Experimental Study On Tachyphylaxis In Psychiatric Patients

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).10
10.31703/gdddr.2023(VIII-II).10
Published : Jun 2023

Abstract

    The objective of the present ex-post facto study is to the prevalence of tachyphylaxis in patients using psychotropic drugs. Method: As a quasi-experimental style of study, 100 participants were purposively selected who were admitted to the rehabilitation centre for the treatment of substance-induced disorders, Psychotic disorders, Bipolar disorder and other psychiatric disorders and being treated... Details

    Tachyphylaxis, Rothschild Scale for Antidepressant Tachyphylaxis (RSAT), Anti- Psychotic medication

    (1) Abid Khan
    M.Phil. Psychology, Department of Pharmacy, SZABIST University, Islamabad Campus, Pakistan.
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11 - Drug vs Self-Care Management of Gestational Diabetes Mellitus: Knowledge and Pra

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).11
10.31703/gdddr.2023(VIII-II).11
Published : Jun 2023

Abstract

    Gestational diabetes mellitus is a significant and growing global health issue. Objectives: To assess the knowledge of women attending antenatal clinics in Faisalabad regarding GDM and its self‐care management practices. Methodology: A descriptive cross‐sectional study. The study's duration was 4 months from February 2023 to May 2023 and study setting areas included Allie... Details

    Knowledge GDM, Self‐Care and Management Practices

    (1) Maham Riaz
    General Nurse, Children Hospital Faisalabad, Punjab, Pakistan.
    (2) Rabia Fazeelat
    General Nurse, Children Hospital Faisalabad, Punjab, Pakistan.
    (3) Shazia Kousar
    General Nurse, Allied Hospital Faisalabad, Punjab, Pakistan.
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12 - Albumin Overview and Its Purification Method

http://dx.doi.org/10.31703/gdddr.2023(VIII-II).12
10.31703/gdddr.2023(VIII-II).12
Published : Jun 2023

Abstract

    Drug researchers are currently studying the use of nanoparticles in drug delivery in great detail. In general, a medication's pharmacokinetic and tissue appropriation profiles can be changed, intracellular infiltration and appropriation can be improved, and a drug's absorption can be improved by dispersing the drug via the epithelium. The ability of nanoparticulate frameworks to tolerate physiolog... Details

    Nanoparticles, Pharmacokinetic, Intracellular Infiltration, Liposomes

    (1) Bushra Rehman
    Assistant Professor, Rahman Medical Institute, Peshawar, KP, Pakistan.
    (2) Hira Ikram
    Lecturer, Institute Biotechnology and Microbiology, Bacha Khan University, Charsadda, KP, Pakistan.
    (3) Rabia Nasir
    Assistant Professor, Center of Excellence in Marine Biology, Karachi, Sindh, Pakistan.
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